Banff Lesion Score i (interstitial Inflammation in non-scarred areas of the cortex). A, Interstitial inflammation in non-scarred areas of the cortex. This Banff Lesion Score, often a marker of TCMR, ranges from 0 to 3, based on the percentage of non-scarred cortex involved, and is usually dominated by mononuclear cells in the case of Acute TCMR. Note the contrast between the non-infiltrated interstitium in the right half of the micrograph and the infiltrate in the edema between the tubules on the left (long arrow). PAS, original magnification x400. B, An example of plasma cell rich interstitial inflammation. If the infiltrate comprises more than 5% to 10% of either eosinophils, neutrophils or plasma cells an asterisk is added to the Banff Lesion Score i (e.g. i1*). H&E, hematoxylin and eosin, original magnification x400.